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Monitoring of clonal evolution of acute myeloid leukemia identifies the leukemia subtype, clinical outcome and potential new drug targets for post-remission strategies or relapse

In cases of treatment failure in acute myeloid leukemia (AML), the utility of mutational profiling in primary refractoriness and relapse is not established. We undertook a perspective study using next-generation sequencing (NGS) of clinical follow-up samples (n=91) from 23 patients with AML with the...

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Detalhes bibliográficos
Principais autores: Esther Onecha, Inmaculada Rapado, María Luz Morales, Gonzalo Carreño-Tarragona, Pilar Martinez-Sanchez, Xabier Gutierrez, José María Sáchez Pina, María Linares, Miguel Gallardo, Joaquín Martinez-López, Rosa Ayala
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2020-07-01
coleção:Haematologica
Acesso em linha:https://haematologica.org/article/view/9837
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