Exploration of the effect of Celastrol on protein targets in nasopharyngeal carcinoma: Network pharmacology, molecular docking and experimental evaluations

Background: Celastrol, an important extract of Tripterygium wilfordii, shows strong antitumor activity in a variety of tumors including nasopharyngeal carcinoma (NPC). However, little is known about its targets in NPC. We aimed to screen the key gene targets of Celastrol in the treatment of NPC by m...

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Principais autores:	Junjun Ling, Yu Huang, Zhen Sun, Xiaopeng Guo, Aoshuang Chang, Jigang Pan, Xianlu Zhuo
格式:	Artigo
语言:	Inglês
出版:	Frontiers Media S.A. 2022-11-01
丛编:	Frontiers in Pharmacology
主题:	Celastrol nasopharyngeal carcinoma drug targets network pharmacolgy traditional Chinese medicine
在线阅读:	https://www.frontiersin.org/articles/10.3389/fphar.2022.996728/full
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