Origin and Evolution of Two Independently Duplicated Genes Encoding UDP- Glucose: Glycoprotein Glucosyltransferases in Caenorhabditis and Vertebrates

UDP- glucose: glycoprotein glucosyltransferase (UGGT) is a protein that operates as the gatekeeper for the endoplasmic reticulum (ER) quality control mechanism of glycoprotein folding. It is known that vertebrates and Caenorhabditis genomes harbor two uggt gene copies that exhibit differences in the...

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Principais autores:	Diego A. Caraballo, Lucila I. Buzzi, Carlos P. Modenutti, Ana Acosta-Montalvo, Olga A. Castro, María S. Rossi
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Oxford University Press 2020-02-01
סדרה:	G3: Genes, Genomes, Genetics
נושאים:	udp- glucose: glycoprotein glucosyltransferase caenorhabditis elegans vertebrates purifying selection positive selection neofunctionalization
גישה מקוונת:	http://g3journal.org/lookup/doi/10.1534/g3.119.400868
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