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Antigen-presenting cell internalization is key for understanding and evaluating therapeutic antibodies’ immunogenicity

Therapeutic antibodies have revolutionized the treatment of many diseases. However, their safety and efficacy are often altered by their immunogenicity, as many patients frequently develop anti-drug antibodies. Dendritic cells (DCs) are the most potent antigen-presenting cells of the immune system....

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Hlavní autoři: Maria Lteif, Marc Pallardy, Isabelle Turbica
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2025-09-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1617395/full
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