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ChREBPβ is dispensable for the control of glucose homeostasis and energy balance

Impaired glucose metabolism is observed in obesity and type 2 diabetes. Glucose controls gene expression through the transcription factor ChREBP in liver and adipose tissues. Mlxipl encodes 2 isoforms: ChREBPα, the full-length form (translocation into the nucleus is under the control of glucose), an...

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Principais autores: Emeline Recazens, Geneviève Tavernier, Jérémy Dufau, Camille Bergoglio, Fadila Benhamed, Stéphanie Cassant-Sourdy, Marie-Adeline Marques, Sylvie Caspar-Bauguil, Alice Brion, Laurent Monbrun, Renaud Dentin, Clara Ferrier, Mélanie Leroux, Pierre-Damien Denechaud, Cedric Moro, Jean-Paul Concordet, Catherine Postic, Etienne Mouisel, Dominique Langin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical investigation 2022-02-01
coleção:JCI Insight
Assuntos:
Metabolism
Acesso em linha:https://doi.org/10.1172/jci.insight.153431
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