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Evaluating the effects of glutaraldehyde concentration and incubation time on the structural integrity of the human pericardium

BackgroundGlutaraldehyde (GA) fixation of pericardial tissue is widely used in bioprosthetic heart valves. However, how GA concentration and incubation time jointly influence structure-function relationships remains incompletely understood. This study systematically evaluates the effects of GA conce...

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Principais autores: Sahra Tasdelen, Gianluca Dimonte, Irna Cutuk, Andreas Teuschl-Woller, Thomas Poschner, Severin Laengle, Viktoriia Tymoshenko, Barbara Messner, Thomas Augustin, Lena Hirtler, Martin Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-06-01
coleção:Frontiers in Bioengineering and Biotechnology
Assuntos:
biomaterials
cardiac surgery
mechanical properties
pericardium
tissue processing
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fbioe.2026.1746518/full
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