Functional and biochemical protection by combined N-acetylcysteine and D-methionine in guinea pig noise-induced hearing loss

Abstract Purpose This study examined whether combining antioxidants could enhance protection and permit lower dosing for treating noise-induced hearing loss (NIHL). The therapeutic effects of D-methionine (DMET) and N-acetylcysteine (NAC) were evaluated in a guinea pig model. Methods Ninety-six guin...

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Hlavní autoři:	Po-Hsuan Wu, Nicholas Cheng, Wu-Chia Lo, Chih-Ming Chang, Po-Wen Cheng, Shing-Hwa Liu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2026-01-01
Edice:	Head & Face Medicine
Témata:	N-acetylcysteine D-methionine Noise Hearing loss Antioxidant
On-line přístup:	https://doi.org/10.1186/s13005-026-00588-z
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