Anti-Cancer Stem-like Cell Compounds in Clinical Development – An Overview and Critical Appraisal.

Cancer stem-like cells (CSC) represent a subpopulation of tumor cells with elevated tumor-initiating potential. Upon differentiation, they replenish the bulk of the tumor cell population. Enhanced tumor-forming capacity, resistance to antitumor drugs, and metastasis-forming potential are the hallmar...

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Detalhes bibliográficos

Principais autores:	Fabrizio eMarcucci, Cristiano eRumio, François eLefoulon
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2016-05-01
coleção:	Frontiers in Oncology
Assuntos:	Classification Epithelial-Mesenchymal Transition therapy biomarkers Clinical development Cancer stem-like cells
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00115/full
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