Compliance of extended infusion of piperacillin/tazobactam with the desired pharmacokinetic/pharmacodynamic index in septic patients

Background/Aim. Piperacillin (PIP)/tazobactam (TAZ) –PIP/TAZ is a beta-lactam antibiotic used to treat Gram-negative sepsis. The portion of the dosing interval during which antibiotic concentrations are above the minimal inhibitory concentration – MIC (fT>MIC) or, even more, four times higher than t...

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Hlavní autoři:	Tomić Nataša, Vukmirović Saša, Sabo Stanislav, Uvelin Arsen, Popović Radmila, Vicković Sanja, Tomić Ljiljana, Tomić Zdenko
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2025-01-01
Edice:	Vojnosanitetski Pregled
Témata:	beta lactam antibiotics chromatography high pressure liquid drug resistance microbial infusion intravenous pharmacokinetics pharmacology sepsis
On-line přístup:	https://doiserbia.nb.rs/img/doi/0042-8450/2025/0042-84502500029T.pdf
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