Single-cell transcriptional profiling in osteosarcoma and the effect of neoadjuvant chemotherapy on the tumor microenvironment

Osteosarcoma (OS), a malignant tumor, originates from the bone marrow. Currently, treatment for OS remains limited, making it urgent to understand the immune response in the tumor microenvironment of patients with OS. A comprehensive bioinformatics analysis was performed, including cell clustering s...

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Detalhes bibliográficos

Principais autores:	Xiao-yu He, Liu-yi Que, Fan Yang, Yi Feng, Dong Ren, Xiang Song
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-06-01
coleção:	Journal of Bone Oncology
Assuntos:	Osteosarcoma scRNA-seq Tumor microenvironment Tumor-infiltrating lymphocytes Myeloid cells
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2212137424000848
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