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Transcriptomic dynamics and cell-to-cell communication during the transition of prospermatogonia to spermatogonia revealed at single-cell resolution

Abstract Background Spermatogonia are essential for the continual production of sperm and regeneration of the entire spermatogenic lineage after injury. In mammals, spermatogonia are formed in the neonatal testis from prospermatogonia (also termed gonocytes), which are established from primordial ge...

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Principais autores: Zhen He, Rong-Ge Yan, Qin-Bang Shang, Qi-En Yang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-01-01
Serier:BMC Genomics
Fag:
Prospermatogonia
Spermatogonia
Fate decisions
Single-cell RNA-seq
Transcription regulator
Online adgang:https://doi.org/10.1186/s12864-025-11244-2
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