Bridging prediction and reality: Comprehensive analysis of experimental and AlphaFold 2 full-length nuclear receptor structures

AlphaFold 2 has revolutionized protein structure prediction, yet systematic evaluations of its performance against experimental structures for specific protein families remain limited. Here we present the first comprehensive analysis comparing AlphaFold 2-predicted and experimental nuclear receptor...

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Detalhes bibliográficos

Principais autores:	Akerke Mazhibiyeva, Tri T. Pham, Karina Pats, Martin Lukac, Ferdinand Molnár
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-01-01
coleção:	Computational and Structural Biotechnology Journal
Assuntos:	AlphaFold 2 Nuclear receptors Structural comparison Conformational diversity Domain architecture Prediction accuracy
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2001037025001734
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