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A Myeloid Lineage Signifying Anti-tumor Necrosis Factor Resistance in Crohn’s DiseaseSummary

Background & Aims: Although anti-tumor necrosis factor (TNF) therapy has improved Crohn’s disease (CD) management, the development of a refractory phenotype having resistance to the drug is not uncommon. The mechanisms behind this anti-TNF nonresponse are unknown but are likely multifactorial. H...

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Furkejuvvon:
Váldodahkkit: Sachith Munasinghe, Duke Geem, Kodhai Duraiarasan, Sushma C. Maddipatla, Shanta Murthy, Yeonjoo Hwang, Ranjit S. Pelia, Murugadas Anbazhagan, Garima Sharma, Vikram Koti, Irina Geiculescu, Barbara J. Niklinsa-Schirtz, Cary Sauer, Raghavan Chinnadurai, Vasantha L. Kolachala, Jason D. Matthews, Subra Kugathasan
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Elsevier 2026-01-01
Ráidu:Cellular and Molecular Gastroenterology and Hepatology
Fáttát:
Anti-TNF
CD47
Inflammatory Bowel Disease
Refractory Crohn’s Disease
SIRPα
Liŋkkat:http://www.sciencedirect.com/science/article/pii/S2352345X25001778
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