Protocol to induce and assess cGAS-STING pathway activation in vitro

Summary: The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway plays a pivotal role in several cellular processes including pathogen recognition and inflammatory responses. We describe a protocol to activate the cGAS-STING pathway in murine cells using nucleic acids trans...

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Autors principals:	Hanane Chamma, Soumyabrata Guha, Nadine Laguette, Isabelle K. Vila
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2022-06-01
Col·lecció:	STAR Protocols
Matèries:	Cell Biology Immunology Molecular Biology Gene Expression Signal Transduction Molecular/Chemical Probes
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2666166722002647
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