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Genetic variants in DBC1, SIRT1, UCP2 and ADRB2 as potential biomarkers for severe obesity and metabolic complications

IntroductionObesity is a multifactorial disease associated with the development of many comorbidities. This disease is associated with several metabolic alterations; however, it has been shown that some individuals with obesity do not exhibit metabolic syndrome. Adipose tissue neutralizes the detrim...

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Main Authors: Ana Carolina Proença da Fonseca, Izadora Sthephanie da Silva Assis, Kaio Cezar Rodrigues Salum, Lohanna Palhinha, Gabriella de Medeiros Abreu, Verônica Marques Zembrzuski, Mario Campos Junior, José Firmino Nogueira-Neto, Amanda Cambraia, Mauro Lucio Ferreira Souza Junior, Clarissa Menezes Maya-Monteiro, Pedro Hernán Cabello, Patrícia Torres Bozza, João Regis Ivar Carneiro
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Genetics
Subjects:
DBC1
SIRT1
biomarkers
severe obesity
metabolic complications
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1363417/full
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