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Role of SQSTM1/p62 in regulating Mallory-Denk body in alcohol-associated liver disease

Background Alcohol-associated liver disease (ALD) is a global health problem without an effective treatment. Mallory-Denk body (MDB) is a protein aggregate commonly found in alcohol-associated hepatitis (AH). MDB primarily contains ubiquitinated proteins, cytokeratin 8 and sequestosome 1 (SQSTM1)/p6...

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Autori principali: Zhaoli Sun, Wen-Xing Ding, Hong-Min Ni, Brandon Peiffer, Kaitlyn Hinz, Hui Qian
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2025-11-01
Serie:eGastroenterology
Accesso online:https://egastroenterology.bmj.com/content/3/4/e100262.full
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