Salicylate Inhibits Thrombopoiesis in Rat Megakaryocytes by Changing the Membrane Micro-Architecture

Background/Aims: Salicylate causes drug-induced immune thrombocytopenia. However, some clinical studies indicate the presence of additional mechanisms in the drug-induced thrombocytopenia, by which the platelet production from megakaryocytes may directly be affected. Since salicylate is amphiphilic...

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Detalhes bibliográficos

Principais autores:	Itsuro Kazama, Asuka Baba, Yasuhiro Endo, Hiroaki Toyama, Yutaka Ejima, Mitsunobu Matsubara, Masahiro Tachi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cell Physiol Biochem Press GmbH & Co KG 2015-04-01
coleção:	Cellular Physiology and Biochemistry
Assuntos:	Salicylate Megakaryocytes Membrane capacitance Thrombopoiesis Membrane micro-architecture
Acesso em linha:	http://www.karger.com/Article/FullText/374039
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