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Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key?

Before the discovery of peroxisome proliferator activated receptors (PPARs), it was well known that certain drugs considered as classical PPAR-alpha agonists induced hepatocarcinoma or peroxisome proliferation in rodents. These drugs were derivatives of fibric acid, and they included clofibrate, bez...

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書誌詳細
主要な著者: Roberto Scatena, Patrizia Bottoni, Bruno Giardina
フォーマット: Artigo
言語:Inglês
出版事項: Wiley 2008-01-01
シリーズ:PPAR Research
オンライン・アクセス:http://dx.doi.org/10.1155/2008/256251
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