Decreased Insulin Sensitivity in Telomerase-Immortalized Mesenchymal Stem Cells Affects Efficacy and Outcome of Adipogenic Differentiation in vitro

Modern biomedical science still experiences a significant need for easy and reliable sources of human cells. They are used to investigate pathological processes underlying disease, conduct pharmacological studies, and eventually applied as a therapeutic product in regenerative medicine. For decades,...

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Detalhes bibliográficos

Principais autores:	Konstantin Kulebyakin, Pyotr Tyurin-Kuzmin, Anastasia Efimenko, Nikita Voloshin, Anton Kartoshkin, Maxim Karagyaur, Olga Grigorieva, Ekaterina Novoseletskaya, Veronika Sysoeva, Pavel Makarevich, Vsevolod Tkachuk
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-08-01
coleção:	Frontiers in Cell and Developmental Biology
Assuntos:	mesenchymal stem/stromal cells osteogenic differentiation chondrogenic differentiation adipogenic differentiation insulin signaling protein kinase A signaling
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcell.2021.662078/full
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