Ontogenetic stage and type of donor cells shape extracellular vesicles’ therapeutic potential for osteoarthritis

Abstract Background Osteoarthritis (OA) remains an intractable condition due to the limited regenerative capacity of adult cartilage. Extracellular vesicles (EVs) have emerged as promising therapeutics, yet the optimal donor cell source is still undetermined, as both donor cell type and age signific...

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Detalhes bibliográficos

Principais autores:	K. Tarasova, M.B. Arteaga, A. Kidtiwong, H. Nivarthi, J. Gamauf, G. Corso, S. Gültekin, A. Bileck, M. Rothbauer, S. Toegel, M. Hackl, S. Kau-Strebinger, C. Gerner, R. Grillari, I. Gerner, F. Jenner
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-09-01
coleção:	Stem Cell Research & Therapy
Assuntos:	Extracellular vesicle Chondrocyte Synoviocytes Fetal Perinatal Osteoarthritis
Acesso em linha:	https://doi.org/10.1186/s13287-025-04585-y
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