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Early Dyskinesias in Parkinson’s Disease Patients With Parkin Mutation: A Primary Corticostriatal Synaptopathy?

Mutations in the PARKIN gene cause early-onset Parkinson’s disease (PD). Despite the high proportion of still missing phenotyping data in the literature devoted to early-onset PD, studies suggest that, as compared with late-onset PD, PARKIN patients show dystonia at onset and extremely dose-sensitiv...

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Hlavní autoři: Jenny Sassone, Flavia Valtorta, Andrea Ciammola
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019-03-01
Edice:Frontiers in Neuroscience
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On-line přístup:https://www.frontiersin.org/article/10.3389/fnins.2019.00273/full
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