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Titanium catalyzed [2σ + 2π] cycloaddition of bicyclo[1.1.0]-butanes with 1,3-dienes for efficient synthesis of stilbene bioisosteres

Abstract Natural stilbenes have shown significant potential in the prevention and treatment of diseases due to their diverse pharmacological activities. Here we present a mild and effective Ti-catalyzed intermolecular radical-relay [2σ + 2π] cycloaddition of bicyclo[1.1.0]-butanes and 1,3-dienes. Th...

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Príomhchruthaitheoirí: Yonghong Liu, Zhixian Wu, Jing-Ran Shan, Huaipu Yan, Er-Jun Hao, Lei Shi
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Nature Portfolio 2024-05-01
Sraith:Nature Communications
Rochtain ar líne:https://doi.org/10.1038/s41467-024-48494-9
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