DOT1L suppressed the proliferation of osteosarcoma cell line via modulating SYK/EGFR/P53 and SHP2-induced STING-NLRP3-pyroptosis signaling
Abstract DOT1L, acting as a key epigenetic regulator, plays important roles in various biological processes, offering significant insights for the development of new cancer therapeutic strategies. This study investigates the impact of DOT1L on pyroptosis in osteosarcoma and its molecular mechanisms....
Furkejuvvon:
| Váldodahkki: | |
|---|---|
| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Nature Portfolio
2025-07-01
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| Ráidu: | Scientific Reports |
| Fáttát: | |
| Liŋkkat: | https://doi.org/10.1038/s41598-025-05221-8 |
| Fáddágilkorat: |
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