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Clinical relevance of guanine-derived urinary biomarkers of oxidative stress, determined by LC-MS/MS

A reliable and fast liquid chromatography-tandem mass spectrometry method has been developed for the simultaneous determination of three oxidized nucleic acid damage products in urine, 8-oxoguanine (8-oxoGua), 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodGuo) and 8-oxo-7,8-dihydroguanosine (8-oxoGuo)....

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Bibliografiske detaljer
Principais autores: Ying-Ming Shih, Marcus S. Cooke, Chih-Hong Pan, Mu-Rong Chao, Chiung-Wen Hu
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019-01-01
Serier:Redox Biology
Online adgang:http://www.sciencedirect.com/science/article/pii/S2213231718309509
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