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Differential Modulation of Spinal Angiotensin-Converting Enzymes Plays a Critical Role in the Development of Trigeminal Neuropathic Pain

<b>Background/Objectives:</b> While the functions of angiotensin-converting enzyme (ACE) 1 and 2 are well established in peripheral tissues, the role of the spinal ACE1 and ACE2 pathways in the development of neuropathic pain remains unclear. This study examined the role of the spinal ACE1 and ACE2...

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Autori principali: Jo-Young Son, Yu-Mi Kim, Song-Hee Kang, Jin-Sook Ju, Dong-Kuk Ahn
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2026-05-01
Serie:Pharmaceuticals
Soggetti:
angiotensin
angiotensin converting enzyme
antinociception
trigeminal neuralgia
trigeminal nucleus caudalis
Accesso online:https://www.mdpi.com/1424-8247/19/5/764
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