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Inhibition of DNA Repair by Inappropriate Activation of ATM, PARP, and DNA-PK with the Drug Agonist AsiDNA

AsiDNA is a DNA repair inhibitor mimicking DNA double-strand breaks (DSB) that was designed to disorganize DSB repair pathways to sensitize tumors to DNA damaging therapies such as radiotherapy and chemotherapy. We used the property of AsiDNA of triggering artificial DNA damage signaling to examine...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nathalie Berthault, Ptissam Bergam, Floriane Pereira, Pierre-Marie Girard, Marie Dutreix
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2022-07-01
Saila:Cells
Gaiak:
Sarrera elektronikoa:https://www.mdpi.com/2073-4409/11/14/2149
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