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Iron Oxide Nanoparticles as Carriers for DOX and Magnetic Hyperthermia after Intratumoral Application into Breast Cancer in Mice: Impact and Future Perspectives

There is still a need for improving the treatment of breast cancer with doxorubicin (DOX). In this paper, we functionalized magnetic nanoparticles (MNPs) with DOX and studied the DOX-induced antitumor effects in breast cancer cells (BT474) in the presence of magnetic hyperthermia (43 °C, 1 h). We sh...

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Principais autores: Susann Piehler, Heidi Dähring, Julia Grandke, Julia Göring, Pierre Couleaud, Antonio Aires, Aitziber L. Cortajarena, José Courty, Alfonso Latorre, Álvaro Somoza, Ulf Teichgräber, Ingrid Hilger
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-05-01
coleção:Nanomaterials
Assuntos:
magnetic hyperthermia
magnetic nanoparticles
doxorubicin
breast cancer
mouse model
Acesso em linha:https://www.mdpi.com/2079-4991/10/6/1016
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