Epigenetic modification in liver fibrosis: Promising therapeutic direction with significant challenges ahead

Liver fibrosis, characterized by scar tissue formation, can ultimately result in liver failure. It's a major cause of morbidity and mortality globally, often associated with chronic liver diseases like hepatitis or alcoholic and non-alcoholic fatty liver diseases. However, current treatment options...

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Detalhes bibliográficos

Principais autores:	Runping Liu, Yajing Li, Qi Zheng, Mingning Ding, Huiping Zhou, Xiaojiaoyang Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-03-01
coleção:	Acta Pharmaceutica Sinica B
Assuntos:	Liver fibrosis Epigenetics regulation DNA methylation Histone acetylation Histone methylation mRNA methylation
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211383523004239
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