Procleave: Predicting Protease-specific Substrate Cleavage Sites by Combining Sequence and Structural Information

Proteases are enzymes that cleave and hydrolyse the peptide bonds between two specific amino acid residues of target substrate proteins. Protease-controlled proteolysis plays a key role in the degradation and recycling of proteins, which is essential for various physiological processes. Thus, solvin...

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Detalhes bibliográficos

Principais autores:	Fuyi Li, Andre Leier, Quanzhong Liu, Yanan Wang, Dongxu Xiang, Tatsuya Akutsu, Geoffrey I. Webb, A. Ian Smith, Tatiana Marquez-Lago, Jian Li, Jiangning Song
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2020-02-01
coleção:	Genomics, Proteomics & Bioinformatics
Assuntos:	Protease Cleavage site prediction Machine learning Conditional random field Structural determinants
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S167202292030053X
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