Krüppel‐Like Factors Orchestrate Endothelial Gene Expression Through Redundant and Non‐Redundant Enhancer Networks

Background Proper function of endothelial cells is critical for vascular integrity and organismal survival. Studies over the past 2 decades have identified 2 members of the KLF (Krüppel‐like factor) family of proteins, KLF2 and KLF4, as nodal regulators of endothelial function. Strikingly, inducible...

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Bibliografiska uppgifter

Huvudupphov:	David R. Sweet, Roshan Padmanabhan, Xudong Liao, Himanshu R. Dashora, Xinmiao Tang, Lalitha Nayak, Rajan Jain, Sarah De Val, Vinesh Vinayachandran, Mukesh K. Jain
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Wiley 2023-02-01
Serie:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Ämnen:	27 chromatin endothelial cell enhancer Kruppel‐like factor promoter transcription
Länkar:	https://www.ahajournals.org/doi/10.1161/JAHA.121.024303
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