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Piceatannol and its analogues alleviate Staphylococcus aureus pathogenesis by targeting β-lactamase biofilms and α-hemolysin

Abstract β-Lactamases, biofilms and toxins pose challenges for combating S. aureus infection. Thus, identifying inhibitors that can restore bacterial sensitivity to antibiotics, destroy biofilms, and antitoxins is a promising way to develop alternative agents. In this study, we found that piceatanno...

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Principais autores: Guizhen Wang, Jingyao Wen, Zizeng Tian, Hanbing Zhou, Xinli Peng, Peigang Zhang, Zhandong Li
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-02-01
Serier:Scientific Reports
Fag:
Staphylococcus aureus
Biofilm
β-lactamase
α-hemolysin
Anti-infection
Online adgang:https://doi.org/10.1038/s41598-025-89654-1
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