The Importance of the “Time Factor” for the Evaluation of Inhibition Mechanisms: The Case of Selected HDAC6 Inhibitors

Histone deacetylases (HDACs) participate with histone acetyltransferases in the modulation of the biological activity of a broad array of proteins, besides histones. Histone deacetylase 6 is unique among HDAC as it contains two catalytic domains, an <i>N</i>-terminal microtubule binding region and a...

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Xehetasun bibliografikoak

Egile Nagusiak:	Edoardo Cellupica, Gianluca Caprini, Gianluca Fossati, Doris Mirdita, Paola Cordella, Mattia Marchini, Ilaria Rocchio, Giovanni Sandrone, Andrea Stevenazzi, Barbara Vergani, Christian Steinkühler, Maria Antonietta Vanoni
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2023-07-01
Saila:	Biology
Gaiak:	histone deacetylase histone deacetylase 6 inhibition kinetics medicinal chemistry hydroxamates
Sarrera elektronikoa:	https://www.mdpi.com/2079-7737/12/8/1049
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