Targeted next-generation sequencing for microbial and clinical diagnosis: a prospective controlled comparison between sputum and bronchoalveolar lavage fluid in patients with community-acquired pneumonia

Abstract Background Accurate identification of pathogens causing community-acquired pneumonia (CAP) in adults is a crucial step for successful diagnosis and treatment. However, some patients cannot tolerate bronchoscopy, or bronchoalveolar lavage fluid (BALF) cannot be obtained in a timely manner. C...

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Hauptverfasser:	Xin Feng, Min Du, Shaobin Feng, Yujuan Li, Yin Zhao, Dong Zhang, Xi Yong, Zhuangwen Pu, Jiawei Wu, Jun Niu, Jianming Luo, Yuni Xiang, Tong Chen, Hangyong He
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2026-05-01
Schriftenreihe:	BMC Infectious Diseases
Schlagworte:	Community-acquired pneumonia Bronchoalveolar lavage fluid Sputum Targeted next-generation sequencing
Online-Zugang:	https://doi.org/10.1186/s12879-026-13616-9
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