High prevalence of KRAS and GNAS mutations in pseudomyxoma peritonei underscores opportunities for targeted therapeutic strategies

Pseudomyxoma peritonei (PMP) is a rare, slow-growing cancer with few efficacious treatment options in unresectable cases. Mutations in the KRAS and GNAS oncogenes are common, but the reported frequencies vary greatly, most likely because of low tumor cellularity in peritoneal tumor samples. With tre...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Torgunrud Annette, Lund-Andersen Christin, Davidson Ben, Nitschke Marcussen Ina Katrine, Larsen Stein G., Dagenborg Vegar, Flatmark Kjersti
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	De Gruyter 2025-12-01
Edice:	Pleura and Peritoneum
Témata:	pseudomyxoma peritonei kras mutation gnas mutation oncogenes targeted therapy
On-line přístup:	https://doi.org/10.1515/pp-2025-0034
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!