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Clinical utility of custom-designed NGS panel testing in pediatric tumors

Abstract Background Somatic genetic testing is rapidly becoming the standard of care in many adult and pediatric cancers. Previously, the standard approach was single-gene or focused multigene testing, but many centers have moved towards broad-based next-generation sequencing (NGS) panels. Here, we...

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Principais autores: Lea F. Surrey, Suzanne P. MacFarland, Fengqi Chang, Kajia Cao, Komal S. Rathi, Gozde T. Akgumus, Daniel Gallo, Fumin Lin, Adam Gleason, Pichai Raman, Richard Aplenc, Rochelle Bagatell, Jane Minturn, Yael Mosse, Mariarita Santi, Sarah K. Tasian, Angela J. Waanders, Mahdi Sarmady, John M. Maris, Stephen P. Hunger, Marilyn M. Li
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-05-01
coleção:Genome Medicine
Assuntos:
Tumor sequencing
Molecular profiling
Pediatric cancer
Acesso em linha:http://link.springer.com/article/10.1186/s13073-019-0644-8
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