Maternal Under- and Over-Nutrition during Gestation Causes Islet Hypertrophy and Sex-Specific Changes to Pancreas DNA Methylation in Fetal Sheep

The mechanisms by which fetal programming predisposes offspring to reduced β-cell function later in life are poorly understood. We hypothesized that maternal under- and over-nutrition during gestation would negatively affect offspring pancreas development and alter DNA methylation patterns. Pregnant...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Maria Peterson, Mary Gauvin, Sambhu Pillai, Amanda Jones, Katelyn McFadden, Katelynn Cameron, Sarah Reed, Steven Zinn, Kristen Govoni
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	MDPI AG 2021-08-01
سلاسل:	Animals
الموضوعات:	beta cell function fetal programming DNA methylation endocrine pancreas sheep
الوصول للمادة أونلاين:	https://www.mdpi.com/2076-2615/11/9/2531
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!