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Toxicity in the era of immune checkpoint inhibitor therapy

Immune checkpoint inhibitors (ICIs) reinvigorate anti-tumor immune responses by disrupting co-inhibitory immune checkpoint molecules such as programmed cell death 1 (PD-1) and cytotoxic T lymphocyte antigen 4 (CTLA-4). Although ICIs have had unprecedented success and have become the standard of care...

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Hoofdauteurs: Synat Keam, Naimah Turner, Fernanda G. Kugeratski, Rene Rico, Jocelynn Colunga-Minutti, Rayansh Poojary, Sayan Alekseev, Anisha B. Patel, Yuanteng Jeff Li, Ajay Sheshadri, Monica E. Loghin, Karin Woodman, Ashley E. Aaroe, Sarah Hamidi, Priyanka Chandrasekhar Iyer, Nicolas L. Palaskas, Yinghong Wang, Roza Nurieva
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2024-08-01
Reeks:Frontiers in Immunology
Onderwerpen:
immune related adverse events
immune checkpoint
preclinical model
immunotherapy
treatment
Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1447021/full
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