Adenine methylation is very scarce in the Drosophila genome and not erased by the ten-eleven translocation dioxygenase

N6-methyladenine (6mA) DNA modification has recently been described in metazoans, including in Drosophila, for which the erasure of this epigenetic mark has been ascribed to the ten-eleven translocation (TET) enzyme. Here, we re-evaluated 6mA presence and TET impact on the Drosophila genome. Using a...

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Detalles Bibliográficos

Principais autores:	Manon Boulet, Guerric Gilbert, Yoan Renaud, Martina Schmidt-Dengler, Emilie Plantié, Romane Bertrand, Xinsheng Nan, Tomasz Jurkowski, Mark Helm, Laurence Vandel, Lucas Waltzer
Formato:	Artigo
Idioma:	Inglês
Publicado:	eLife Sciences Publications Ltd 2023-12-01
Series:	eLife
Assuntos:	DNA methylation epigenetics N6-methyladenine (6mA) ten-eleven translocation (TET) liquid chromatography coupled with mass tandem mass spectrometry (LCMS/ MS) single-molecule real-time sequencing (SMRT-seq)
Acceso en liña:	https://elifesciences.org/articles/91655
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