Genetic interaction of DISC1 and Neuroligin in regulation of glutamatergic synaptogenesis

Synaptic development and functionality have been considered as fundamental mechanisms underlying a range of neuropsychiatric disorders, including schizophrenia. Emerging evidence from biological and clinical studies implicates mutations in the Disrupted-in-Schizophrenia-1 (DISC1) gene in the pathoge...

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Principais autores:	Takato Honda, Himani Pandey, Akira Sawa, Katsuo Furukubo-Tokunaga
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-05-01
Colecção:	Frontiers in Neuroscience
Assuntos:	DISC1 genetics molecular and biological psychiatry Neuroligin schizophrenia synapse
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fnins.2026.1832180/full
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