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CIP2A mediates fibronectin-induced bladder cancer cell proliferation by stabilizing β-catenin

Abstract Background Fibronectin (FN) is associated with tumorigenesis and progression in bladder cancer, however, the underlying mechanisms causing this remain largely unknown. Furthermore, cancerous inhibitor of protein phosphatase 2A (CIP2A) has been shown to play important regulatory roles in can...

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Principais autores: Fengbin Gao, Tianyuan Xu, Xianjin Wang, Shan Zhong, Shanwen Chen, Minguang Zhang, Xiaohua Zhang, Yifan Shen, Xiaojing Wang, Chen Xu, Zhoujun Shen
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2017-05-01
Serier:Journal of Experimental & Clinical Cancer Research
Fag:
Bladder cancer
Fibronectin
CIP2A
β-catenin
Proliferation
Online adgang:http://link.springer.com/article/10.1186/s13046-017-0539-8
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