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Ferulic acid restores mitochondrial dynamics and autophagy via AMPK signaling pathway in a palmitate-induced hepatocyte model of metabolic syndrome

Abstract Mitochondrial dysfunction, characterized by elevated oxidative stress, impaired energy balance, and dysregulated mitochondrial dynamics, is a hallmark of metabolic syndrome (MetS) and its comorbidities. Ferulic acid (FA), a principal phenolic compound found in whole grains, has demonstrated...

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Hlavní autoři: Yitong Li, Weiyang Zhao, Ali Tahir Sair, Tong Li, Rui Hai Liu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2024-08-01
Edice:Scientific Reports
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On-line přístup:https://doi.org/10.1038/s41598-024-66362-w
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