CD4+ levels control the odds of induction of humoral immune responses to tracer doses of therapeutic antibodies.

Rapidly increasing number of therapeutic antibodies are being repurposed to imaging probes for noninvasive diagnosis, as well as monitoring during treatment or disease recurrence. Though antibody-based imaging involves tracer doses (~3 log lower than therapeutic doses), and immune responses are seve...

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Detalhes bibliográficos

Principais autores:	Sharat Srinivasula, Erin Gabriel, Insook Kim, Paula DeGrange, Alexis St Claire, Candace Mallow, Robert E Donahue, Chang Paik, H C Lane, Michele Di Mascio
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2017-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC5679608?pdf=render
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