Failure to Thrive: Impaired BDNF Transport along the Cortical–Striatal Axis in Mouse Q140 Neurons of Huntington’s Disease

Boosting trophic support to striatal neurons by increasing levels of brain-derived neurotrophic factor (BDNF) has been considered as a target for therapeutic intervention for several neurodegenerative diseases, including Huntington’s disease (HD). To aid in the implementation of such a strategy, a t...

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Autori principali:	Michael T. Maloney, Wei Wang, Sumana Bhowmick, Ivan Millan, Mridu Kapur, Nicolas Herrera, Everett Frost, Elena Y. Zhang, Scott Song, Melissa Wang, Amelia Bora Park, Annabelle Y. Yao, Yanmin Yang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2023-01-01
Serie:	Biology
Soggetti:	Huntington’s disease Q140 mice brain-derived neurotrophic factor medium spiny neuron cortical–striatal axis
Accesso online:	https://www.mdpi.com/2079-7737/12/2/157
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