Bone Mechanoregulation Allows Subject-Specific Load Estimation Based on Time-Lapsed Micro-CT and HR-pQCT in Vivo

Patients at high risk of fracture due to metabolic diseases frequently undergo long-term antiresorptive therapy. However, in some patients, treatment is unsuccessful in preventing fractures or causes severe adverse health outcomes. Understanding load-driven bone remodelling, i.e., mechanoregulation,...

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Bibliografische Detailangaben

Hauptverfasser:	Matthias Walle, Francisco C. Marques, Nicholas Ohs, Michael Blauth, Ralph Müller, Caitlyn J. Collins
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2021-06-01
Schriftenreihe:	Frontiers in Bioengineering and Biotechnology
Schlagworte:	bone loading estimation mechanoregulation finite element analysis bone remodelling human distal radius mouse caudal vertebra
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fbioe.2021.677985/full
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