Adenosine in human atrial fibrillation modulates and re-distributes atria-wide dominant frequencies and directs to reentry ablation sites with improved outcome

Abstract Understanding and therapy of persistent atrial fibrillation (AF) are suboptimal partly because the dynamics, mapping, and ablation of rotational activity that has been proposed to drive AF remain elusive. In the present work we challenge AF with Adenosine, an agonist activating the Kir3.x s...

Descrición completa

Detalles Bibliográficos

Principais autores:	David Calvo, Lucia Salinas, Pablo Martínez-Camblor, María Salgado, Ruth Álvarez-Velasco, Amaia Martínez-León, Minel Soroa, Daniel García-Iglesias, David Filgueiras-Rama, Juan José Gonzalez-Ferrer, Victoria Cañadas, Ricardo Salgado, Alba Cruz, Jorge Quintanilla, Andrés Redondo, Miguel Rodrigo, Julián Pérez-Villacastín, Nicasio Pérez-Castellano, Omer Berenfeld
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2025-12-01
Series:	Scientific Reports
Assuntos:	Persistent atrial fibrillation Adenosine Dominant frequency Reentry Rotor Ablation
Acceso en liña:	https://doi.org/10.1038/s41598-025-26262-z
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!