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Generation of multidrug resistant human tissues by overexpression of the ABCG2 multidrug transporter in embryonic stem cells.

The ABCG2 multidrug transporter provides resistance against various endo- and xenobiotics, and protects the stem cells against toxins and stress conditions. We have shown earlier that a GFP-tagged version of ABCG2 is fully functional and may be used to follow the expression, localization and functio...

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Detalles Bibliográficos
Principais autores: Zsuzsa Erdei, Anita Schamberger, György Török, Kornélia Szebényi, György Várady, Tamás I Orbán, László Homolya, Balázs Sarkadi, Ágota Apáti
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC5896897?pdf=render
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