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Importance of finding the bona fide target of the Fanconi anemia pathway

Abstract Fanconi anemia (FA) is a rare genetic disease characterized by the deficiency of the cellular response and repair pathway for DNA interstrand crosslink (ICL) damage. Although recent studies have revealed the detailed molecular functions of FA proteins encoded by 22 genes, the mechanism of o...

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Príomhchruthaitheoirí: Wataru Sakai, Kaoru Sugasawa
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2019-03-01
Sraith:Genes and Environment
Ábhair:
Rochtain ar líne:http://link.springer.com/article/10.1186/s41021-019-0122-y
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