Current status of immunodeficient mouse models as substitutes to reduce cat and dog use in heartworm preclinical research [version 1; peer review: 2 approved]

Chemoprophylactic prevention of veterinary heartworm disease in companion animals, caused by the vector-borne nematode parasite Dirofilaria immitis, is a multi-billion-dollar global market. Experimental use of cats and dogs in preclinical heartworm drug testing is increasing due to evolving drug-res...

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Principais autores:	Joseph D Turner, Mark J Taylor, John W McCall, Scott McCall, Abdelmoneim Mansour, Crystal Fricks, Utami DiCosty, Jessica L Dagley
Formato:	Artigo
Idioma:	Inglês
Publicado:	F1000 Research Ltd 2024-05-01
Series:	F1000Research
Assuntos:	Dirofilariasis heartworm parasitology anthelmintic anti-parasitic drugs eng
Acceso en liña:	https://f1000research.com/articles/13-484/v1
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