The Crosstalk between GPR81/IGFBP6 Promotes Breast Cancer Progression by Modulating Lactate Metabolism and Oxidative Stress

Breast cancer is the most frequent tumor and the leading cause of cancer deaths in women. In recent years, lactate metabolism and, in particular, its receptor GPR81 have been shown to play a vital role in cancer biology. GPR81 is upregulated in breast cancer and promotes tumor growth by tumor cell-d...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Lucia Longhitano, Stefano Forte, Laura Orlando, Stephanie Grasso, Alessandro Barbato, Nunzio Vicario, Rosalba Parenti, Paolo Fontana, Angela M. Amorini, Giuseppe Lazzarino, Giovanni Li Volti, Michelino Di Rosa, Arcangelo Liso, Barbara Tavazzi, Giacomo Lazzarino, Daniele Tibullo
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-01-01
Schriftenreihe:	Antioxidants
Schlagworte:	lactate IGFBP6 GPR81 oxidative stress breast cancer
Online-Zugang:	https://www.mdpi.com/2076-3921/11/2/275
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