Search for promising antiparkinsonian agents among monoterpene-bearing azaadamantanes

Parkinson’s disease (PD) involves degeneration of nigrostriatal dopaminergic neurons with a consequent imbalance across multiple neurotransmitter systems regulating basal ganglia function. Amantadine (AMD; 1-aminoadamantane) is a low-affinity, uncompetitive NMDA receptor antagonist and a modulator o...

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Auteurs principaux:	M. P. Pitukhin, I. V. Sorokina, S. V. Aydagulova, K. Yu. Ponomarev, K. N. Sorokina, T. G. Tolstikova, E. V. Suslov, K. P. Volcho
Format:	Artigo
Langue:	Russo
Publié:	Russian Academy of Sciences, Siberian Branch Publishing House 2026-03-01
Collection:	Сибирский научный медицинский журнал
Sujets:	parkinson’s disease amantadine azaadamantanes mptp-induced parkinsonism haloperidol-induced catalepsy arecoline-induced tremor
Accès en ligne:	https://sibmed.elpub.ru/jour/article/view/2722
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